Typically, the Home page is going to be the most visited page of your site. And if your site is like most, the Home page design will be different from the layout of the interior pages. Don't neglect these interior pages as important sources of revenue. While no one interior page is likely to come close to the amount of traffic you receive on the Home page, added together, the interior pages will be significant drivers of traffic and revenue.
You don't need to build a huge site, online magazine or Web-based TV station to make money selling online ads. You can sell ads on practically any site at all, no matter how many pages or how much traffic you get. It's a good way to make a few extra bucks without having to do much work at all.